Open AccessMyeloradiculitis with lupus-like autoimmunity following Sinovac COVID-19 vaccination
Author(s) -
Yew Long Lo,
Jack Lam,
Ling Ling Chan
Publication year - 2021
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.138
H-Index - 16
ISSN - 1823-6138
DOI - 10.54029/2021eyv
Subject(s) - medicine , transverse myelitis , autoimmunity , immunology , anti nuclear antibody , vaccination , pathogenesis , myelitis , systemic lupus erythematosus , covid-19 , antibody , virology , pathology , multiple sclerosis , spinal cord , autoantibody , infectious disease (medical specialty) , disease , psychiatry
We report a 67 year old man with features in keeping with transverse myelitis, lumbar root and cauda equina involvement suggestive of delayed autoimmune pathogenesis after the Sinovac COVID-19 vaccination previously observed in vaccines containing viral antigens. Grossly elevated antinuclear antibody and anti-double-stranded DNA are in line with observations in lupus myelitis despite the lack of systemic manifestations.