Open Access
Testicular Cancer - An Unexpected Course of the Disease
Author(s) -
Marija Gamulin
Publication year - 2021
Language(s) - English
DOI - 10.53902/sojmccr.2021.01.000507
Subject(s) - seminoma , teratoma , malignancy , somatic cell , choriocarcinoma , pathology , adenocarcinoma , medicine , cancer , immature teratoma , sarcoma , germ cell tumors , biology , chemotherapy , biochemistry , gene
There are two major histologic types of testicular cancer: pure seminoma and nonseminomatous germ cell tumours which include embryonic carcinoma, choriocarcinoma, yolc sac tumours and teratomas. Rarely, in 2% of cases, teratomas may contain elements of somatic cancer, such as sarcoma or adenocarcinoma and it is then referred to as a ''teratoma with somatic type malignancy''. The histology of somatic malignant elements most commonly includes adenocarcinoma and various types of sarcomas; however, so far as the primitive neuroectodermal tumors (PNETs) are concerned the experience is quite limited. Here we report an unusual case of a testicular seminoma that relapsed 6 months after surgery as a teratoma with somatic neuroendocrine differentiation situated in retroperitoneal lymph nodes.