Open AccessEvaluation of Ten Trace Elements in Riedel’s Struma Using Neutron Activation Analysis
Author(s) -
Vladimir Zaichick
Publication year - 2021
Language(s) - English
DOI - 10.53902/mrccp.2021.01.000502
Subject(s) - thyroid , neutron activation analysis , medicine , thyroid disease , nuclear medicine , chemistry , endocrinology , radiochemistry , pathology
Aims: Role of trace elements (TE) in etiology and pathogenesis of Riedel’s disease (RD) is unclear. The aim of this exploratory study was to assess whether there were significant changes in thyroid tissue levels of ten TE (Ag, Co, Cr, Fe, Hg, Rb, Sb, Sc, Se, and Zn) are present in the fibrotic transformed thyroid. Methods: Ten TE of thyroid tissue were determined in 6 patients with RD and 105 healthy populations. The measurements were performed using non-destructive instrumental neutron activation analysis with high resolution spectrometry of long-lived radionuclides. Results: Elevated mean values of Rb content were found in thyroid with RD in comparison with normal level. Conclusions: There are considerable changes in Rb content in tissue of thyroid with RD. Thus, it is reasonable to assume that the level of Rb in thyroid tissue can be used as RD markers. However, this topic needs additional studies.