Open AccessRisk Factors for Reintubation Related to Non-Airway Failure After Liver Transplantation in Intensive Care Unit: Observational Study
Author(s) -
Ana Paula Agostini,
Ilka de Fátima Santana Ferreira Boin,
Aline Maria Heidemann,
Rodrigo Marques Tonella,
Antônio Luis Eiras Falcão,
Lígia dos Santos Roceto Ratti,
Luciana Castilho de Figueirêdo,
Luíz Cláudio Martins
Publication year - 2022
Publication title -
brazilian journal of transplantation
Language(s) - English
Resource type - Journals
ISSN - 2764-1589
DOI - 10.53855/bjt.v25i1.425_en
Subject(s) - medicine , liver transplantation , intensive care unit , receiver operating characteristic , mechanical ventilation , pneumonia , sofa score , confidence interval , odds ratio , intensive care , transplantation , intensive care medicine
1Braz J Tranpl■v25 n1■e0222■2022Abstract: The aim of this observational study was to evaluate the risk factors and predictive indexes of reintubation in patients after liver transplantation in the intensive care unit of a university hospital. The time at the intensive care unit, time on mechanical ventilation, use of noninvasive ventilation, ventilator-associated pneumonia, mortality, sequential organ failure assessment scores (SOFA), simplified acute physiology score (SAPS 3), model for end-stage liver disease (MELD), Child-Pugh (CHILD), Acute Physiology and Chronic Health Disease Classification System II (APACHE II), and balance of risk score (BAR) were correlated with reintubation. The following tests were used for the statistical analysis: Kolmogorov-Smirnov, χ2, Student’s t-test, and regression analysis and receiver operating characteristic (ROC) curve. Two hundred and thirty-seven individuals were analyzed. Among them, 38 (16%) were reintubated. The comparative analysis was performed between reintubated and non-reintubated individuals. The variables analyzed – ventilator associated pneumonia, death, mechanical ventilation time, intensive care unit time, noninvasive ventilation use, MELD score, SAPS 3, BAR, and SOFA third days – after liver transplantation were significantly different (p 0.70. High values of the BAR score were considered risk factors for reintubation in this study. SOFA third day showed moderate discriminatory power in predicting reintubation after liver transplantation.