Open AccessBURKITT’S LYMPHOMA IN KIDNEY: A RARE ENTITY.
Author(s) -
Muhammad Mohsin Riaz,
Arous Khaqan,
Omer Sabir
Publication year - 2021
Publication title -
pakistan journal of kidney diseases
Language(s) - English
Resource type - Journals
eISSN - 2708-3020
pISSN - 2617-0329
DOI - 10.53778/pjkd5477
Subject(s) - lymphoma , medicine , chromosomal translocation , incidence (geometry) , burkitt's lymphoma , population , pathology , epidemiology , immunology , biology , gene , biochemistry , physics , environmental health , optics
Burkitt’s Lymphoma is an aggressive form of Non-Hodgkin’s Lymphoma, with higher incidence in children comprising 30% of pediatric lymphoma. The hallmark of which is a translocation involving c-MYC gene on chromosome 8. Burkitt’s Lymphoma comprises of 6.35% of all lymphoma cases in Pakistan, with male predominance. Lymphoma rarely presents as a primary pathology of acute kidney injury. Burkitt’s lymphoma in adult population is uncommon and few cases have been reported where Burkitt’s lymphoma presents as a cause of acute kidney injury. There are three epidemiological subtypes Endemic (African), sporadic (non-endemic) and immunodeficiency related. Sporadic cases dominate amongst others in Pakistan.