Open AccessAssessment of relationship of markers of the protective system of the oral cavity and the tubulointersticial system of the kidney
Author(s) -
Usmanova Shoira Ravshanbekovna,
Yuldasheva Nasiba Alisherovna,
Daminova Nargiza Ravshanovna
Publication year - 2022
Publication title -
international journal of health sciences (ijhs) (en línea)
Language(s) - English
Resource type - Journals
eISSN - 2550-6978
pISSN - 2550-696X
DOI - 10.53730/ijhs.v6ns4.6019
Subject(s) - lysozyme , lactoferrin , kidney , urine , medicine , saliva , cystatin c , lipocalin , pathology , kidney disease , urinary system , biology , renal function , biochemistry
The features of markers of the protective system of saliva, blood and urine in patients with tubulointerstitial kidney damage were studied in a comparative aspect. For this study, 58 patients were selected with chronic kidney disease, namely tubulointerstitial kidney disease. In the blood, oral fluid and urine, the content of lysozyme, the level of lactoferrin, cystatin and lipocalin-2 were determined by the enzyme immunoassay. It was found that somatic pathology affects both the frequency of occurrence of pathology of hard dental tissues and the clinical picture of the course of major dental diseases. It is noted that a sensitive marker of tubulointerstitial kidney damage is a study in saliva, blood and urine of the activity of lysozyme, lipocalin, cystatin and lactoferrin, which will make it possible to propose therapeutic and prophylactic measures for patients with tubulointerstitial kidney damage.