Open AccessN-acetyl-cysteine effect on total antioxidant capacity in Iraqi men with oligoasthenoteratozoospermia
Author(s) -
Fatima Sinan Salman,
Huda I. Al–Qadhi,
Baraa Abd Alkareem
Publication year - 2022
Publication title -
international journal of health sciences (ijhs) (en línea)
Language(s) - English
Resource type - Journals
eISSN - 2550-6978
pISSN - 2550-696X
DOI - 10.53730/ijhs.v6ns3.6034
Subject(s) - antioxidant capacity , antioxidant , infertility , spermatogenesis , male infertility , medicine , cysteine , sperm , andrology , chemistry , physiology , biology , biochemistry , pregnancy , enzyme , genetics
The aim of this prospective study is to evaluate the effect of using N-acetyl cysteine (600mg/day) for 3 consecutive months on the serum level of total antioxidant capacity of Iraqi males with idiopathic infertility. This study was performed at infertile center of ALKUT hospital during the period from October 2021 to March 2022 .A total 45 patients with idiopathic oligoasthenoteratozoospermia were received N-acetyl cysteine (NAC) for 12 weeks, their total antioxidant capacity (TAC) was measured at the baseline and after 12 weeks. The results showed that TAC levels were significantly higher (0.61±0.02 vs. 0.86±0.02 ; LSD= 0.10 ) which confirmed that NAC has positive effect in increasing the level of antioxidant capacity in infertile men and thus decreasing the reactive oxygen species ROS and restore the oxidant balance level resulting in better spermatogenesis and sperm function.