
Molecular docking, synthesis and biological evaluation of some Imidazo-thiadiazole based Chalcone derivatives as potent triple mutant T790M/C797S EGFR inhibitors
Author(s) -
Abhinandan A. Alman,
Vishal Soni,
Suresh G. Killedar
Publication year - 2022
Publication title -
international journal of health sciences (ijhs) (en línea)
Language(s) - English
Resource type - Journals
eISSN - 2550-6978
pISSN - 2550-696X
DOI - 10.53730/ijhs.v6ns2.8781
Subject(s) - t790m , chemistry , chalcone , cytotoxicity , docking (animal) , egfr inhibitors , mutant , stereochemistry , in vitro , hydrogen bond , combinatorial chemistry , molecule , epidermal growth factor receptor , biochemistry , receptor , organic chemistry , medicine , gefitinib , nursing , gene