Open AccessRelationship of fibroblast growth factor 23 (FGF23) to antioxidants and lipid level in patients with kidney diseases
Author(s) -
Hanan A. Ahmed,
Nawal Th. Younis
Publication year - 2022
Publication title -
international journal of health sciences (ijhs) (en línea)
Language(s) - English
Resource type - Journals
eISSN - 2550-6978
pISSN - 2550-696X
DOI - 10.53730/ijhs.v6ns2.6300
Subject(s) - arylesterase , medicine , malondialdehyde , ceruloplasmin , triglyceride , endocrinology , chemistry , very low density lipoprotein , cholesterol , lipoprotein , biochemistry , oxidative stress , pon1 , genotype , gene
The research involved study the relation between FGF23 and some of the biochemical parameters related to the chronic kidney disease (Glutathion GSH and arylesterase ARE enzymes,ceruloplasmin ,Malondialehyde ,glucose ,cholesterol ,triglyceride ,LDL ,VLDL,HDL)in serum blood patients compared with control group,the result demonstration is a significant increase in the mean concentration rate FGF23 was (324.06± 291.1 pg/ml) in patients compared with mean concentration in control group was ( 273 ± 188.5 pg/ml) , also the result showed a significant increase in the concentration of (ceruloplasmin,malondialdehyde ,cholesterol ,LDL) and a significant decrease had been shown in the concentration of (reduced Glutathion,arylesterase,HDL).while the results had been showed a non significant increase with (glucose,triglyceride,VLDL) in patients compared with control group, Correlation coefficient of FGF23 with these clinical parameters showed a positive significant correlation with(Malondialdehyde) while the result showed a non significant correlation with rest of the biochemical parameters.