Randomized Control Trial (RCT) Hatha Yoga online efficacy for D5 Dopamine Receptor mRNA expression and mRNA nuclear factor activated Kappa B cell (NF-κB) mRNA expression in Peripheral Lymphocyte Cell in adolescence whose suffering internet addiction durin

Internet addiction become higher problem during pandemic COVID-19 because of a lot of use internet activity. Adolescences is the highest population whose suffer for Internet Addiction. Hatha Yoga had been studied could reduce of internet addiction in adolescents, however have not understand how does its work in biology molecular perspectives. We developed yoga capsule program for Adolescence whose suffering internet addiction, to evaluate effect D5 Dopamine Receptor mRNA expression and Nuclear Factor Activated Kappa B Cell (NF-κB) mRNA expression in peripheral lymphocyte cell. Adolescent whose suffer Internet addiction are recruited from senior high school. After internet addiction assessment using Internet Addiction Test Indonesian version (IAT-Ina), 34 adolescents divided into 2 group with random allocation became Hatha Yoga Group and Control Group. Sample advised 60 minutes and three times per week on 8 weeks program, led by Yoga instructor certified. Before and post intervention all participant had check D5 Dopamine receptor mRNA Expression and NF-κB mRNA expression in peripheral lymphocyte cell and also IAT-Ina score. Hatha Yoga Online allows treatment for internet addiction in adolescent during pandemic COVID-19 and future. Forthcoming result may contribute about Hatha Yoga could affect the biology molecular to reduce symptoms and sign in Internet addiction.