Open AccessCircle fitting of boundaries of microarray spots
Author(s) -
R. S. Veena,
Shalini Shravan,
Vidyadevi G. Biradar,
V Prashanth
Publication year - 2022
Publication title -
international journal of health sciences (ijhs) (en línea)
Language(s) - English
Resource type - Journals
eISSN - 2550-6978
pISSN - 2550-696X
DOI - 10.53730/ijhs.v6ns1.6023
Subject(s) - radius , boundary (topology) , metric (unit) , mathematics , circumference , differential (mechanical device) , mathematical analysis , geometry , computer science , physics , engineering , operations management , computer security , thermodynamics
A new circle fitting algorithm is presented that generates the best circle to approximate the boundary of a given microarray spot. Here, the best approximation means, the total differential area between the circumference of the circle and the boundary of the spot is kept minimum. The center and the radius of the circle are determined to satisfy this condition. The differential area is used as a quantitative metric to represent the boundary quality of the corresponding microarray spot.