Open AccessFormulation and Evaluation of Herbal Gel Containing Kigelia africana(lam.) Benth., Fruits Extract
Author(s) -
R Bhramaramba,
M.Harsha vardahan chowdary,
k.Bharath lova,
A Nagarjuna
Publication year - 2015
Publication title -
journal of advance research in applied science
Language(s) - English
Resource type - Journals
ISSN - 2208-2352
DOI - 10.53555/nnas.v2i4.680
Subject(s) - paraben , traditional medicine , triethanolamine , shampoo , bark (sound) , irritation , preservative , medicine , chemistry , toxicology , food science , biology , chromatography , organic chemistry , ecology , analytical chemistry (journal) , immunology
Herbal medicine has become an item of global importance both medicinal and economical. Although usage of these herbal medicines has increased, their quality, safety and efficiency are serious concerns in industrialized and developing countries. The present research has been undertaken with the aim to formulate and evaluate the herbal gel containing Kigelia africana(Lam.) Benth., fruits extract. The gel formulation was designed by using Carbapol 940, Kigelia africana(Lam.) Benth., fruits extract, propylene glycol, methyl paraben, propyl paraben and required amount of distilled water. The skin pH (6.8-7.1) was maintained by drop wise addition of Triethanolamine. The physicochemical Parameters of formulations (pH, Spreadibility, Stability etc.) were determined. Stability studies have carried out as per ICH guidelines for 3 months at different temperatures and humidity. The results showed that formulation ontaining Kigelia africana(Lam.) Benth., fruits extract Show better stability. Further formulations have studied for skin irritation on animal model (Rat) and result showedthat there was no skin irritation to animals.