Open AccessSynthesis of 8-Methoxyquinoline-5-Amino Acetic Acid and its Herbicidal Potential
Author(s) -
E Adewole,
Oke O.T.,
Ojo A.
Publication year - 2015
Publication title -
journal of advance research in applied science
Language(s) - English
Resource type - Journals
ISSN - 2208-2352
DOI - 10.53555/nnas.v2i4.679
Subject(s) - acetic acid , quinoline , chemistry , absorption (acoustics) , amino acid , organic chemistry , materials science , biochemistry , composite material
The quinoline skeleton is often used for the design of many synthetic compounds with diverse pharmacological properties. 8-Methoxyquinoline 5-amino acetic acid was synthesized from coupling of monochloroacetic acid with 5-amino-8-methoxyquinoline. The IR showed – OH stretch absorption and amino group (-NH) which is not too prominent at 3450cm-1 and 3300cm-1, carbonyl (C=O) absorption depicts at 1614cm-1. The herbicidal activity of the synthesized compound was tested on the weeds and after 11 days of application, the weeds have dried completely indicating the efficacy of the compound.