Open AccessClinical and Biochemical Factors of Portosystemic Encephalopathy in Cirrhosis
Author(s) -
Himayat Ullah,
Muhammad Ashraf,
Raza Ullah,
Shahida Na .,
Jawad Ashraf
Publication year - 2022
Publication title -
pakistan journal of medical and health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.114
H-Index - 7
ISSN - 1996-7195
DOI - 10.53350/pjmhs2216450
Subject(s) - medicine , hepatic encephalopathy , cirrhosis , encephalopathy , gastroenterology , confidence interval , logistic regression , electrolyte imbalance , portosystemic shunt , portal hypertension
Aim: Responsible factors in patients with portosystemic encephalopathy and their relation with the severity of encephalopathy using “west haven scoring”. Methods: This cross-sectional study was done in the Gastroenterology Department, Hayatabad Medical Complex Peshawar. After ethical approval, a sample of 500 patients was calculated by universally accepted sample calculators. 95% confidence intervals and 5%margin of error. The sample was taken by a non-probability consecutive sampling technique. Results: Out of 500 patients, 307 were male and 193 females. The mean age was 57.36(±17.65 SD). Electrolyte imbalance (79.2%) was the most prevalent responsible factor, followed by infection (47.4%) and dehydration (24.4%). The number of patients with Grade 1, 2, 3 and 4 encephalopathy were 48, 187, 223, 42 respectively. In the majority of patients with encephalopathy, more than one responsible factor was present. Conclusion: Portosystemic encephalopathy is one of the most serious and life-threatening complications of liver failure and cirrhosis. Keywords: Portosystemic encephalopathy, responsible factors, gastrointestinal bleeding.