Open AccessNeurological Deficits of Coronavirus Disease-19: A Systematic Literature Review
Author(s) -
Fawaz Al- Hussain,
Muhammad Hashim Ghouri,
Zouina Sarfraz,
Noor Ul Falah,
Saima Tabassum,
Ambreen Anjum,
Mah Rukh
Publication year - 2022
Publication title -
pakistan journal of medical and health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.114
H-Index - 7
ISSN - 1996-7195
DOI - 10.53350/pjmhs221637
Subject(s) - neurology , medicine , covid-19 , disease , medline , pandemic , cohort study , coronavirus , pathophysiology , cohort , intensive care medicine , pediatrics , psychiatry , pathology , infectious disease (medical specialty) , political science , law
Aim: To review neurological aspects of patients infected with COVID-19 including neurological dysfunctions and possible pathophysiology. Methods: A systematic review of articlesfrom PubMed, Ovid MEDLIN, DOAJ databases and grey literature included the WHO-COVID-19 database, and medRxiv.Articles published from January 2020 until June 2020 were included in the review. Out of the226 titles and abstracts, 213 were identified after the removing duplicates. With a screening of 119 studies carried by all authors, 83 full-text articles were assessed based on inclusion criteria of the neurological perspectives with COVID-19. Subsequently, 45 texts were removed. A total of 38 studies were included in the last scrutiny.Specifically, case reports, cohort studies, and case series were included Results: Reviewed evidence was presented in textual and tabulated format, which includes methodology, characteristics of included studies and summary of findings. Correlational evidence of COVID-19 disease and neurological dysfunctions with possible pathophysiology isreviewed. Conclusion:The findings provide evidence for physicians and neurologists working with COVID-19 patients about the possible probable complications and clinical presentations due to the SARS-CoV-2 infection. Keywords: COVID-19; SARS-CoV-2; Coronavirus Disease; Respiratory illness; Neurology; Nervous system; Critical Illness;