Open AccessOutcomes of Oxidative Stress in Spontaneous Miscarriage. A Cross-Sectional Clinical Prospective Study
Author(s) -
Aniqa Shahid,
. Fakharunissa,
Qamarunissa Muhabat,
Zainab Maqsood
Publication year - 2022
Publication title -
pakistan journal of medical and health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.114
H-Index - 7
ISSN - 1996-7195
DOI - 10.53350/pjmhs22163495
Subject(s) - miscarriage , oxidative stress , reactive oxygen species , superoxide dismutase , catalase , glutathione peroxidase , medicine , antioxidant , gestation , glutathione , hemoglobin , andrology , pregnancy , obstetrics , gastroenterology , endocrinology , chemistry , biochemistry , enzyme , biology , genetics
Aims and Objectives: The aims and objectives of current study were to investigate biological role of enzymatic antioxidants against reactive oxygen species in normal and recent spontaneous miscarriage pregnant women. Results: In control group mean standard deviation (mean ±SD), of blood serum levels regarding age, number of spontaneous miscarriages, hemoglobin, random glucose levels, catalase, superoxide dismutase, glutathione peroxidase were (24.8±23.7, 0.00±0.01, 15.4± 2.41, 135.95±3.12, 106.97 ± 13.94, 12.96±1.71, 12.50 ± 6.5) whereas in study group these biomarkers showed a remark able significant (P<0.005) changes such as (25.1±13.7, 2.10±10.01, 13.14± 12.11,145.65±7.10, 98.89 ± 12.84, 10.06±0.11, 7.20 ± 1.0) respectively. Conclusion: The results of this study claimed that in study group the concentration of reactive oxygen species were higher than the enzymatic antioxidants which is a prediction of spontaneous miscarriages in pregnant women. Keywords: Spontaneous miscarriage, Enzymatic antioxidants, Reactive oxygen species, Gestation