Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B | Zendy

José D. Debes | Zendy; Gertine van Oord | Zendy; André Boonstra | Zendy

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Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B

Author(s) -

José D. Debes,

Gertine van Oord,

André Boonstra

Publication year - 2020

Publication title -

annals of global health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.602

H-Index - 66

ISSN - 2214-9996

DOI - 10.5334/aogh.2866

Subject(s) - medicine , hbsag , point of care testing , hepatitis b virus , whole blood , point of care , rapid diagnostic test , blood test , hepatitis b , test (biology) , diagnostic test , virology , immunology , emergency medicine , virus , pathology , biology , paleontology

We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all genotypes other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensitivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.

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