z-logo
open-access-imgOpen Access
Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
Author(s) -
James Leathers,
María Belén Pisano,
Viviana Elizabeth Ré,
Gertine van Oord,
Amir Sultan,
André Boonstra,
José D. Debes
Publication year - 2019
Publication title -
annals of global health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.602
H-Index - 66
ISSN - 2214-9996
DOI - 10.5334/aogh.2562
Subject(s) - hbsag , medicine , diagnostic test , hepatitis b , chronic hepatitis , liver disease , limited resources , virology , immunology , hepatitis b virus , pediatrics , risk analysis (engineering) , virus
Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here