Diagnostic Accuracy of FOBT and Colorectal Cancer Genetic Testing: A Systematic Review & Meta-Analysis | Zendy

Abdul Rahman Ramdzan | Zendy; Muhammad Aklil Abd Rahim | Zendy; Aznida Mohamad Zaki | Zendy; Zuraidah Zaidun | Zendy; Azmawati Mohammed Nawi | Zendy

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Diagnostic Accuracy of FOBT and Colorectal Cancer Genetic Testing: A Systematic Review & Meta-Analysis

Author(s) -

Abdul Rahman Ramdzan,

Muhammad Aklil Abd Rahim,

Aznida Mohamad Zaki,

Zuraidah Zaidun,

Azmawati Mohammed Nawi

Publication year - 2019

Publication title -

annals of global health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.602

H-Index - 66

ISSN - 2214-9996

DOI - 10.5334/aogh.2466

Subject(s) - meta analysis , medicine , colorectal cancer , colonoscopy , oncology , cancer , fecal occult blood , population , environmental health

Colorectal cancer (CRC) is the second leading cause of cancer related death in the world after lung cancer. Early detection of CRC leads to improvement in cancer survival rate. In recent years, efforts have been made to discover a non-invasive screening marker of higher sensitivity and specificity. Fecal occult blood testing (FOBT) and genetic testing become alternative modalities to screen CRC in the population other than colonoscopy. The aim of this systematic review and meta-analysis is to determine the diagnostic accuracy, sensitivity and specificity of FOBT and genetic testing as screening tools in colorectal cancer.

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