Open Access
Fibrogénesis hepática células estelares hepáticas
Author(s) -
Osiris G Ildefonso García,
Alma Aurora Ramírez Hernández,
Jovito César Santos Álvarez,
Juan M Velázquez Enriquez,
Gabriel Carrasco Torres,
Verónica Rocío Vásquez-Garzón,
Rafael Baltierrez Hoyos
Publication year - 2018
Publication title -
tequio
Language(s) - English
Resource type - Journals
eISSN - 2594-0546
pISSN - 2594-0538
DOI - 10.53331/teq.v1i2.5077
Subject(s) - extracellular matrix , hepatic stellate cell , liver disease , fibrosis , inflammation , chronic liver disease , hepatic fibrosis , liver fibrosis , disease , pathology , chemistry , cancer research , microbiology and biotechnology , biology , medicine , immunology , biochemistry , cirrhosis
Liver fibrosis affects both the amount and the composition of the extracellular matrix. This process may occur during chronic liver disease characterized by hepato biliary disease or inflammation. There is now considerable evidence to support the role of the hepatic stellar cells (HSC) as the main matrix producing cells in fibrogenesis. The focus of this review is to provide insight into hepatic stellar cells in the fibrogenic process.