Open AccessProfile of gestational syphilis in the state of Paraná between 2010 and 2018
Author(s) -
Mariana Rie Hayashida,
Michely Mika Hirota,
Nathália Nakase Mizoguti,
Fernanda Yuki Ito,
Maryna Rodrigues Gonçalves,
Mayara Rodrigues Gonçalves,
Acácia Maria Lourenço Francisco Nasr
Publication year - 2020
Publication title -
dst
Language(s) - English
Resource type - Journals
eISSN - 2177-8264
pISSN - 0103-4065
DOI - 10.5327/dst-2177-8264-20203215
Subject(s) - medicine , syphilis , obstetrics , gestational age , pregnancy , incidence (geometry) , pediatrics , gestation , regimen , observational study , gynecology , human immunodeficiency virus (hiv) , surgery , immunology , physics , biology , optics , genetics
Gestational syphilis is responsible for increased fetal morbidity and mortality. It is related to intrauterine and neonatal complications, with vertical transmission being the most severe outcome. Screening and treatments are part of the prenatal routine. Objective: To describe the profile of gestational syphilis by state, regional incidence, time of diagnosis and treatment. Methods: Quantitative, descriptive, and observational study developed with secondary data from the National System of Notification of Disorders (Sistema de Informação de Agravos de Notificação – SINAN), to evaluate the variables: region, trimester of diagnosis and treatment of gestational syphilis. Results: Between 2010–2018, Paraná recorded 12,011 cases of gestational syphilis, corresponding to 8.5 per 1,000 live births. There was an increase in the number of cases across the state. Among infected pregnant women, most were between 20–29 years old (50.6%). Of the diagnoses, 43.6% were performed in the first trimester of pregnancy and 26.6% in the second. The most widely used treatment regimen was benzathine penicillin G 7,200,000 IU (63.7%). Conclusion: There was an increase in gestational syphilis in Paraná, however, there was greater effectiveness in diagnosis and treatment, with greater detection in the first trimester of pregnancy and prevalence of use of benzathine penicillin G. The study highlights the importance of correct clinical management and early detection, measures that prevent vertical transmission.