Open Access18-FDG PET ANALYSYS FOR DEMENTIA DIAGNOSIS- BASELINE RESULTS FROM A REFERENCE CENTER IN RECIFE, BRAZIL
Author(s) -
Júlia Xavier Ramos,
Bruno Felipe Vieira Zacarias,
Breno Barbosa,
Simone Cristina Soares Brandão
Publication year - 2021
Language(s) - English
Resource type - Conference proceedings
DOI - 10.5327/1980-5764.rpda061
Subject(s) - dementia , dementia with lewy bodies , differential diagnosis , medicine , frontotemporal dementia , neurology , positron emission tomography , diagnostic accuracy , radiology , psychiatry , disease , pathology
Background: Positrons emission tomography associated with computed tomography- PET/CT using the 18 F-fluorodeoxyglucose is a well-established exam for the medical evaluation of dementia, mainly helping in differential diagnosis to determine the specific type of dementia. Objectives: To describe the role of the PET/CT in the differential diagnosis of dementia in patients. Methods: a single-center, descriptive and records-based analysis of patients with Dementia evaluated in a clinic of Neurology at Recife and referred to PET/ CT due to diagnosis uncertainty, between 2020-2021. Results: 29 patients were included. The mean age was 65 years-old and 62% were female. Alzheimer’s dementia was the main diagnostic hypothesis (41.3%). PET/CT was suggestive of Alzheimer’s in 24%, Frontotemporal dementia in 21% and Lewy Bodies Dementia in 17% of patients. PET/CT results disagreed from clinical hypothesis in 21% o and in 10% it was inconclusive. In 38% it corroborated the clinical suspicion. Conclusions: in this sample the use of PET/CT FDG contributed to improve diagnostic accuracy in a significant subset of patients, mostly in the scenery of diagnostic uncertainty or atypical syndromes such as earlyonset dementias. A larger sample size and the continuation of this research will give us more information in the near future.