Open AccessINVESTIGATION OF EPISODIC MEMORY DEFCITS IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT (MCI)
Author(s) -
Eliane Borca Almeida,
Geise Silva,
Isabella B. Avolio,
Camila Dias,
Maira Okada de Oliveira,
Ricardo Nitríni,
Sônia Maria Dozzi Brucki,
Eliane Correa Miotto
Publication year - 2021
Publication title -
dementia and neuropsychologia
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 0.54
H-Index - 21
ISSN - 1980-5764
DOI - 10.5327/1980-5764.rpda043
Subject(s) - episodic memory , recall , audiology , neuropsychology , psychology , cognition , visual memory , population , cognitive psychology , medicine , neuroscience , environmental health
Background: MCI can be classified as amnestic (aMCI) or non-amnestic (naMCI). Patients with aMCI are at increased risk of developing Alzheimer’s disease (AD). The clinical diagnosis encompasses episodic memory decline with preservation of activities of daily living, in addition to possible changes in other cognitive domains. Nevertheless, there is a lack of studies in the Brazilian population comparing the performance of aMCI on different episodic memory tests. Objectives: This study investigated episodic memory alterations in patients with aMCI and healthy controls (HC) through population-validated tests. Methods: We included 54 individuals, 36 aMCI and 18 HC. The neuropsychological protocol included estimated total IQ [vocabulary and matrix reasoning], Logical Memory (LM), Visual Reproduction (VR) and Rey Auditory Verbal Learning Test (RAVLT). Results: Significant differences were found between the groups in LM delayed recall (p=0.048); Visual Memory immediate recall (p=0.002); Visual Memory delayed recall (p=0.006); RAVLT immediate recall (p=0.19); RAVLT delayed recall (p=0.006) and RAVLT recognition (p=0.001). Conclusions: aMCI patients showed significant cognitive deficits in all episodic memory tests, except for the LM immediate recall. These findings corroborate the international literature and indicate the possibility of identifying differential cognitive alterations in the MCI.