Open AccessAPATHY IN FRONTOTEMPORAL DEMENTIA AND PROGRESSIVE SUPRANUCLEAR PALSY: AN EXPLORATORY NEUROIMAGING INVESTIGATION
Author(s) -
Luciano Inácio Mariano,
Leonardo de Souza,
Paulo Caramelli,
Antonio Teixeira Júnior,
Henrique Cerqueira Guimarães,
Elisa de Paula França Resende,
Leandro Boson Gambogi,
Vítor Tumas,
Francisco Cardoso,
Sarah Camargos
Publication year - 2021
Publication title -
dementia and neuropsychologia
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 0.54
H-Index - 21
ISSN - 1980-5764
DOI - 10.5327/1980-5764.rpda018
Subject(s) - apathy , frontotemporal dementia , dementia , physical medicine and rehabilitation , cognition , neuropsychology , medicine , verbal fluency test , progressive supranuclear palsy , clinical trial , randomized controlled trial , disease , rating scale , inclusion and exclusion criteria , physical therapy , psychology , psychiatry , developmental psychology , alternative medicine , pathology
Background: Apathy is a multidimensional syndrome that impairs motivation and mechanisms of behavioural regulation. As apathy is almost ubiquitous in neurodegenerative disorders, understanding the neural basis is required to expand knowledge and ameliorate our instruments. Objective: Verify the feasibility, safety, and adherence of a remote physical and cognitive exercise protocol for elders; and to compare two different protocols and its effects on strength, cognitive functions and well-being. Methods: Use of the PICO strategy, conducted on September 17, on PubMed using “Alzheimer disease” and “diabetes mellitus” as descriptors, identifying 14 articles, selecting 4 after screening. Inclusion criteria: clinical and randomized controlled trials with diabetic and Alzheimer patients, published on the last 5 years. Exclusion criteria: articles focused on medications. Results: Overall adherence to the proposed sessions was 82,36% (sd16,8) in IG and 76,5% (sd24,04) in CG. There were no serious adverse events or drop-outs during the study. There was an improvement in strength and verbal fluency for IG and GDS for both groups (p ≤ 0,05). Conclusion: Both protocols seem a feasible program, reaching an acceptable level of adherence and safety. The technology used can represent a sustainable path for large scale use to promote aging active in developing countries.