Open AccessVasculitis of the central nervous system secondary to amiopathic dermatomyositis: A case report
Author(s) -
Saullo José Silva Rolindo,
Isabela Louise Caldeira Silva,
Samuel Campos Silva,
Denise Sisterolli Diniz
Publication year - 2021
Language(s) - English
Resource type - Conference proceedings
DOI - 10.5327/1516-3180.661
Subject(s) - medicine , vasculitis , dermatomyositis , context (archaeology) , pathology , weakness , hemiparesis , cerebral vasculitis , inflammatory myopathy , stroke (engine) , myalgia , arteritis , lower motor neuron , surgery , motor neuron , lesion , paleontology , mechanical engineering , disease , engineering , biology
Context: Dermatomyositis (DM) is an idiopathic inflammatory myopathy, characterized by proximal skeletal muscle weakness, associated with a variety of characteristic skin manifestations. A form called Amiopathic Dermatomyositis (AD) is a condition that patients have cutaneous findings characteristic of DM without weakness and/or normal muscle enzymes. In turn, central nervous system (CNS) vasculitis refers to a wide spectrum of diseases that result in inflammation and destruction of the blood vessels of the brain, spinal cord and meninges. Case report: Female, 54 years old, reports for 3 months a progressive myalgia, paraparesis and edema in the proximal region of the lower limbs, evolving in the last weeks with erythematous and itchy lesions on the trunk (in shawl), feet and hands, with subsequent peeling of these (mechanic’s hands). During diagnostic investigation she presented epileptic seizures with behavioral arrest, right hemiparesis and motor aphasia. It evolved with a new stroke in the left frontoparietal region. Bilateral angiography showed points of constriction of segments of the middle cerebral artery bilaterally, compatible with CNS vasculitis. Therefore, with the exclusion of other secondary causes of arteritis, associated with the marker of positive inflammatory myopathy (Anti-Jo1) and CPK within the serum levels of normality, the diagnosis of the stroke secondary to AD was closed. Conclusions: Both CNS vasculitis and AD are rare conditions, characteristically diagnoses of exclusion, deserving to be remembered in clinical cases with singular manifestations, as reported in this case.