Probiome: knowing our second genome, the gut microbiota

The gut microbiota a plays an important role in the physiology and pathology of the human body. In recent years, studies are unraveling how the gut microbiota influences not only health and gastrointesPnal disorders, but also other distal organs and systems. Recently, studies are been showing that gut’s bacteria can affect central nervous system physiology and inflammaPon. The gastrointesPnal tract and the nervous system communicate each other through a bidirecPonal signaling network known as brain-intesPne axis. This network is made up of mulPple connecPons that include vagus nerve, immune system and metabolisms, such as metabolites and products derived from intesPnal bacteria. Depression, MulPple Sclerosis, Alzheimer’s, Parkinson’s Disease and AuPsPc Spectrum Disorders are among the most studied neurological condiPons in the gut microbiota field. BiomeHub is a biotechnology StartUP that pioneered the development and performance of analyzes based on cuXngedge genomics and bioinformaPcs technologies applied to microbiology. The company developed the first validated Brazilian intesPnal microbiome test, which all steps are performed in Brazil, in its own infrastructure, using the state of the art in DNA sequencing technologies and analysis of biological data. Probiome is a molecular test capable of detecPng the complex bacteria community that make up the IntesPnal Microbiota, by sequencing the DNA of these bacteria. The growing knowledge accumulaPon about human microbiome allowed rapid advances and it has been building a solid foundaPon for the development of prognoses, diagnoses and clinical intervenPons, while it creates a new paradigm in personalized medicine. Probiome enables a targeted medical and nutriPonal approach through cross-checking between the profile data of the gut microbiota and the paPent clinical condiPons, assisPng in the elaboraPon of more accurate diets and therapies, selecPon of probioPcs and prebioPcs, among other approaches to gut microbiota intervenPons.