Open AccessImpact of meningitis vaccination on mortality and notified cases of the disease in Brazil by region between 2009 and 2019
Author(s) -
Lucca Ribeiro Alves,
Rodrigo Bartolomeu Sobral Neves,
Leonardo Santana Ramos Oliveira
Publication year - 2021
Language(s) - English
Resource type - Conference proceedings
DOI - 10.5327/1516-3180.564
Subject(s) - meningitis , medicine , vaccination , meningococcal meningitis , incidence (geometry) , neisseria meningitidis , meningococcal disease , immunization , pediatrics , meningococcal vaccine , virology , immunology , physics , antigen , biology , bacteria , optics , genetics
Meningitis is a disease with an important history of epidemics during the 20th century. In Brazil, the National Immunization Program (PNI) reduced the general incidence rate of meningitis. However, meningococcal, bacterial,viral and unspecified meningitis are still a challenge in controlling the disease. Objective: Describe data related to vaccination coverage of meningitis, number of deaths and reported cases, between 2009 and 2019, by brazilian region. Design and Setting: Observational study of time series. Methodology: Used secondary data published in DATASUS for the period 2009-2019.The following data were used:Mortality considers deaths from meningitis and meningococcal infection, according to CID- BR-10. Cases were considered by the year of the first symptom and vaccines were evaluated:Meningococcus A/C(MnAC),Meningococcus B/C(MnBC), Meningococcal Conjugate-C (MncC),Meningococcal ACYW1325, Meningococcal B.Proportions were calculated to analyze the trend. Results: 204,211 notifications and 14,562 deaths between 2009 and 2019 were analyzed.The reported cases and deaths from meningitis were decreased by 29% and 34%,respectively.Northeast and Southeast regions stood out with the largest proportional reductions in deaths, with 45% and 37% respectively.For notifications,the Northeast had 54% and the Midwest had a 41% reduction. For Vaccination, all regions had an increase in the period described, with emphasis on the North with an increase of 18,006%,and the Northeast with 30,839%.In addition,the South region increased its applied doses by 499%,with a 4% reduction in deaths,and 10% in notifications. Conclusion:Despite it’s limitations, the analysis suggests the expansion of vaccine coverage contributes positively to the incidence and deaths from meningitis in the Brazilian population.