Open AccessDiagnosis and treatment of Multiple sclerosis: Brazilian and global overview
Author(s) -
Lorrane de Moura Moreira,
Bruna Stefany Alves Françozo,
Bruno Barcelos Pereira,
Camila Almeida Sardinha,
Débora Pimenta Alves,
Filipe Henrique Almeida Barbosa Godoi,
Katherine Oliveira Ferreira,
Silvia Oliveira Dourado
Publication year - 2021
Language(s) - English
Resource type - Conference proceedings
DOI - 10.5327/1516-3180.490
Subject(s) - multiple sclerosis , medicine , ocrelizumab , natalizumab , disease , magnetic resonance imaging , central nervous system , physical medicine and rehabilitation , pathology , immunology , radiology , rituximab , lymphoma
Multiple sclerosis (MS) is a neurodegenerative autoimmune disease of the central nervous system with a chronic, progressive and inflammatory character. In addition, it presents itself in a heterogeneous way, and can be as an isolated syndrome or as a recurrent remitter, in the first stage, or as progressive, in the second stage. The present work was developed with the objective of determining which is the best form of diagnosis and therapy for multiple sclerosis in Brazil. Methods: The review was performed in PubMed platform, with the descriptors: “multiple sclerosis”, “diagnosis”, “therapy” and “research”. Results: The research result in 148 articles. After a criterious reading and the application of the used criteria, was selected 20 articles. Conclusion: For the diagnosis of this chronic neurological disease, magnetic resonance imaging is used to assess myelination of the different regions of the central nervous system, which is the most suitable for the diagnosis of MS. Μoreover, as a complement, cerebrospinal fluid extraction and blood tests are performed in order to ascertain the concentration of B cells. Regarding therapeutics, this is diversified, including drugs, diets and therapies that stimulate cognition and motor action, such as the use of virtual reality programs and motor images. In relation to drugs, it is of importance that SUS makes natalizumab and ocrelizumab available because they are more efficient and enable users to have a better quality of life. Finally, nutritional monitoring is also suggested to establish a ketogenic or fasting diet in a balanced way