Open AccessBurkitt Lymphoma in a HIV infected patient with involvement of cranial nerves
Author(s) -
Clara Sasse Scherer,
Aléxia Zattar,
André Bayerl,
Maria Eduarda Fileti,
Raddib Eduardo Noleto da Nóbrega de Oliveira,
Rafael Pereira Guimarães,
Thábata Emanuelle Martins Nunes,
Gustavo da Cunha Ribas,
Carla Heloísa Cabral Moro,
Alexandre Longo
Publication year - 2021
Language(s) - English
Resource type - Conference proceedings
DOI - 10.5327/1516-3180.035
Subject(s) - medicine , diplopia , context (archaeology) , cranial nerves , lymphoma , aseptic meningitis , dermatology , pediatrics , immunosuppression , surgery , pathology , meningitis , paleontology , biology
Context: Burkitt Lymphoma (BL) is a highly aggressive type of nonHodgkin’s (NHL) B-cell lymphoma and it’s rare in adults. The incidence is increased in those infected with the Human Immunodeficiency Virus (HIV). Endemic, sporadic, and associated with immunodeficiency are its subtypes. The disorder manifests with adenomegalies in several regions, including the Nervous System, and, when cranial nerves are affected, III and VII pairs are more involved. This study aimed to report on a rare case of IV and V cranial nerves pairs involvement caused by BL in a patient with immunosuppression due to HIV infection. Case report: S.A.R., 57 years old, female, diagnosed with HIV and in antiretroviral therapy sought assistance at a public hospital in Joinville. Right axillary lymph node enlargement since 03/20 with biopsy showing atypical lymphocytic infiltrate. On 09/20, she started with perioral paresthesia followed by crises of throbbing right hemicranial headache with dental arch irradiation. Later, she was admitted to the hospital with diplopia for 3 days, night sweats, and unintentional weight loss (2 kg). Skull Magnetic Resonance showed a small periventricular gliosis area and mastoiditis on the right. Main diagnostic hypothesis of BL with trigeminal neuralgia and trochlear palsy on the right. Referred to the intensive care unit, she entered in cardiorespiratory arrest and died. Conclusion: LB evolves rapidly and represents 1 /3 of NHL cases in HIV patients. Despite being an uncommon disease in adults, it’s important to be included in differential diagnosis in clinical presentations, as in the case reported.