Open AccessLocoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy
Author(s) -
Agnès Tallet,
Éric Lambaudie,
Monique Cohen,
Mathieu Minsat,
Marie Bannier,
M. Resbeut,
Gilles Houvenaeghel
Publication year - 2016
Publication title -
world journal of clinical oncology
Language(s) - English
Resource type - Journals
ISSN - 2218-4333
DOI - 10.5306/wjco.v7.i2.243
Subject(s) - medicine , sentinel lymph node , lymph , breast cancer , axillary lymph node dissection , lymph node , biopsy , sentinel node , axillary lymph nodes , dissection (medical) , axillary dissection , general surgery , radiology , oncology , cancer , surgery , pathology
The advent of sentinel lymph-node technique has led to a shift in lymph-node staging, due to the emergence of new entities namely micrometastases (pN1mi) and isolated tumor cells [pN0(i+)]. The prognostic significance of this low positivity in axillary lymph nodes is currently debated, as is, therefore its management. This article provides updates evidence-based medicine data to take into account for treatment decision-making in this setting, discussing the locoregional treatment in pN0(i+) and pN1mi patients (completion axillary dissection, axillary irradiation with or without regional nodes irradiation, or observation), according to systemic treatment, with the goal to help physicians in their daily practice.