Open AccessSurgical strategies in the therapy of non-small cell lung cancer
Author(s) -
F Al-Shahrabani,
Daniel Vallböhmer,
Steffen Angenendt,
Wolfram Trudo Knoefel
Publication year - 2014
Publication title -
world journal of clinical oncology
Language(s) - English
Resource type - Journals
ISSN - 2218-4333
DOI - 10.5306/wjco.v5.i4.595
Subject(s) - medicine , lung cancer , surgical resection , adjuvant therapy , stage (stratigraphy) , neoadjuvant therapy , surgery , disease , cancer , multimodal therapy , oncology , chemotherapy , breast cancer , paleontology , biology
Lung cancer represents the leading cause of cancer mortality worldwide. Despite improvements in preoperative staging, surgical techniques, neoadjuvant/adjuvant options and postoperative care, there are still major difficulties in significantly improving survival, especially in locally advanced non-small cell lung cancer (NSCLC). To date, surgical resection is the primary mode of treatment for stage I and II NSCLC and has become an important component of the multimodality therapy of even more advanced disease with a curative intention. In fact, in NSCLC patients with solitary distant metastases, surgical interventions have been discussed in the last years. Accordingly, this review displays the recent surgical strategies implemented in the therapy of NSCLC patients.