Open AccessResearch Progress on Antibiosis Activity of Scutellaria Flavonoids
Author(s) -
un Yuan Qin,
Wen Xiu Liu,
Xiao Fang Xie,
Peng Cheng
Publication year - 2021
Publication title -
asian journal of complementary and alternative medicine
Language(s) - English
Resource type - Journals
ISSN - 2347-3894
DOI - 10.53043/2347-3894.acam90018
Subject(s) - antibiosis , scutellaria , quorum sensing , traditional medicine , biofilm , efflux , biology , microbiology and biotechnology , chemistry , traditional chinese medicine , biochemistry , medicine , bacteria , genetics , alternative medicine , pathology
Scutellariae (Huangqin) is a traditional medicine that is widely applied in China for the treatment of cold and fever, and nowadays research found that it can against pathogenic microorganism. Flavonoids is the main active constituent isolated from Scutellariae and possesses outstanding antibiosis activity. Scutellaria flavonoids displayed antiseptic actions and anti-resistance, including but not limited to destroy bacterial biofilm, suppressed activity of the DNA enzyme, restrain efflux pump and quorum-sensing system. This paper highlights and discusses the antibiosis activity of Scutellaria flavonoids, along with possible mechanisms of its action. hoping to providing basis and evidence for clinical application.