Open AccessReveal the Relationship Between Hyaluronic Acid and Water Using Aquaphotomics
Author(s) -
Weilu Tian,
Dong Qin,
Boran Lin,
Xiangchun Yang,
Hui Zhang,
Lian Li,
Lei Nie,
Xiaokui Guo,
Siling Huang,
Hengchang Zang
Publication year - 2021
Publication title -
asian journal of complementary and alternative medicine
Language(s) - English
Resource type - Journals
ISSN - 2347-3894
DOI - 10.53043/2347-3894.acam90006
Subject(s) - hyaluronic acid , biochemical engineering , water body , molecule , liquid water , process (computing) , chemistry , computer science , nanotechnology , environmental science , materials science , biology , physics , organic chemistry , environmental engineering , engineering , thermodynamics , genetics , operating system
Hyaluronic acid (HA) is a kind of biological macromolecule with strong water binding ability. It has rich biological functions and plays an important role in the living body. It has extremely high application value in the fields of medical beauty, medicine, medical treatment and food. In the past, the thinking of studying HA was rather rigid, which is reflected in the direct study of HA itself, which is quite difficult in a complex system because there are too many influencing factors in the real biological environment. The proposal of aquaphotomics allows researchers to focus on the water molecules in complex biological systems, which leads us to shift the angle of thinking about HA-related issues to the water molecules that are closely bound to it. In previous and ongoing work, we use spectroscopy technology and aquaphotomics to study water species, focus on the widely used HA and its derivatives on the market, and apply multivariate analysis methods to analyze the interaction between HA and water molecules to further clarify the material properties of HA form the basis for monitoring its process of binding water in the body. This paper briefly reviews important knowledge concerning the relationship between HA and water, and explains our past and ongoing related research in this field. Key words: hyaluronic acid, water, aquaphotomics, spectroscopy