Open AccessOut with the old, in with the new? Case reports of the clinical features and acute management of two novel designer drugs
Author(s) -
Misselbrook Gp,
Hamilton Ej
Publication year - 2012
Publication title -
acute medicine
Language(s) - English
Resource type - Journals
eISSN - 1747-4892
pISSN - 1747-4884
DOI - 10.52964/amja.0566
Subject(s) - phencyclidine , medicine , ingestion , designer drug , recreational drug , acute toxicity , medical emergency , intensive care medicine , recreational use , recreation , pharmacology , drug , toxicity , nmda receptor , receptor , political science , law
Methoxydine (4-MeO-PCP) and Methoxetamine (3-MeO-2-Oxo-PCE) are both commercially produced designer drugs with structural and biochemical similarities to phencyclidine (PCP). Although phencyclidine toxicity is well documented, its recreational use in present times is rare. With the advent of new designer drugs being available widely through internet sites, Acute Physicians should be aware of the clinical features and management of these potential toxins. We present a case of methoxydine ingestion (which to our knowledge has not been previously documented in any medical journals) and a case of methoxetamine ingestion, and discuss their history, contrasting clinical features and acute management.