Open AccessGlomangiopericytoma, three cases in nine days; case reports and Brief review
Author(s) -
M. Patrick Stagg
Publication year - 2022
Publication title -
journal of otolaryngology and rhinology research
Language(s) - English
Resource type - Journals
ISSN - 2693-9282
DOI - 10.52845/jorr/2022/3.1.1
Subject(s) - pathology , dna sequencing , medicine , rare disease , staining , dermatology , biology , disease , dna , genetics
Glomangiopericytoma is a rare sinonasal tumor. We report three casesof this rare disease that presented in nine days to one subspecialt ypractice. Histochemical and DNA sequencing confirmed the diagnosisineachcase.Endoscopicsinonasalsurgeryprovidedcompleteresectionin each case. The occurrence of three cases to one practice withina 2-week timeframe may suggest GPC is under-recognized. Routinesequencing to detect CTNNB1 mutations and staining for smooth muscleactin of suspicious sinonasal tumorsmayincrease the frequencyof GPC detection