Open AccessANTIULCER POTENTIAL OF FICUS DALHOUSIAE STEM BARK METHANOLIC EXTRACT IN ALBINO RATS
Author(s) -
Mohd Firdousuddin Amer Shazia Siddiqa Syed Safiullah Ghori*
Publication year - 2016
Publication title -
zenodo (cern european organization for nuclear research)
Language(s) - English
DOI - 10.5281/zenodo.163851
Subject(s) - ficus , traditional medicine , bark (sound) , biology , botany , medicine , ecology
The aim of the present study was to evaluate the antiulcer potential of Ficus Dalhousiae stem bark methanolic extract by excision and incision experimental models. Aalbino rats weighing 180 - 200 gm were utilised for the study. The preliminary phytochemical screening of the methanolic extract of stem bark showed the presence of various phytoconstituents namely alkaloids, flavanoids glycosides, saponins, sterols and tannins. Aspirin induced and ethanol induced gastric ulcers has been widely used for the experimental evaluation of antiulcer activity. Aspirin induced and ethanol induced gastric lesion formation may be due to stasis in gastric blood flow, which contributes to the development of the hemorrhagic and necrotic aspect of tissue injury, the research justifies that the herbal extract can be effectively used in treatment of ulcers. Key words: Albino rats, methanolic extract, ulcers