COMPARISON OF SERUM PROLACTIN LEVELS IN PATIENTS WITH ERECTILE DYSFUNCTION WITH AND WITHOUT TYPE 2 DIABETES MELLITUS

Prolactin is produced in man in several other tissues like brain, mammary gland, lymphocytes, spleen and thymus. The prolactin receptors are found mainly in the ovary and the mammary glands. Prolactin effects Erectile dysfunction in patients with and without Diabetes Mellitus type 2.   Objective To find out prolactin in erectile dysfunction patients with/without Diabetes Mellitus and compare the difference in prolactin levels of Erectile dysfunction patients across the two groups of diabetic and non-diabetic patients.   Methodology A comparative cross-sectional study was conducted on 100 diabetics and 100 non-diabetic patients to assess the effects of diabetes on erectile dysfunction. A convenience sampling technique was used to select patients from two hospitals. Calibrator measurements were also performed for prolactin. Independent sample t-test was performed for comparison between the two groups.   Results Majority of patients were 40-49 years old (44.5%). Erectile dysfunction (ED) was significantly more common in older age groups. Duration of ED was higher in diabetic patients compared to non-diabetics. Prolactin level was higher in diabetics. Most diabetic and non-diabetic patients (48%) had mild severity of ED, however diabetic patients had slightly more severe form of ED compared to non-diabetics.   Conclusions Erectile dysfunction is generally common in our setting. It may be associated with age and higher levels of prolactin. Moreover, Diabetic patients with erectile dysfunction have more significant deviation of these hormones as compared to their non-diabetic counterparts.