Antioxidant and Antidiabetic Potential of Saponin Fraction Isolated from Moringa oleifera Leaves | Zendy

Fatma Hussain | Zendy; Fatima Ikram | Zendy

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Antioxidant and Antidiabetic Potential of Saponin Fraction Isolated from Moringa oleifera Leaves

Author(s) -

Fatma Hussain,

Fatima Ikram

Publication year - 2020

Publication title -

biological sciences - pjsir

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.117

H-Index - 5

eISSN - 2223-2567

pISSN - 2221-6421

DOI - 10.52763/pjsir.biol.sci.63.2.2020.86.92

Subject(s) - moringa , chemistry , dpph , saponin , antioxidant , flavonoid , fractionation , food science , polyphenol , traditional medicine , chromatography , biochemistry , medicine , alternative medicine , pathology

To assess total phenolic contents, total flavonoid contents (TPC, TFC), DPPH scavenging and antidiabetic (antiglycation and alpha amylase hindrance) activities of Moringa oleifera (MO) leaves, bio- assay guided fractionation was used with thin layer chromatography profile to isolate saponin fraction (SF). The TPC and TFC were 9.7-12.8 GAE and 5.3-9.3 CE (g/100 g dry weight), respectively and aqueous and methanol fractions were more effective. DPPH scavenging activity ranged 69.5-83.1%. SF displayed noteworthy antioxidant ability (p 0.198), nullifying its concentration dependent impact.

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