Open AccessModification of serum proteins in guinea pigs immunized and challenged with toluene diisocyanate
Author(s) -
Angelo M. De Marzo,
Laura Jovine,
Paolo Rizzotti,
Paola Cassetti,
Pierà Boschetto,
Deborah Miotto,
Marina Saetta,
Piero Maestrelli,
C. E. Mapp
Publication year - 2000
Publication title -
scandinavian journal of work, environment and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.621
H-Index - 103
eISSN - 1795-990X
pISSN - 0355-3140
DOI - 10.5271/sjweh.525
Subject(s) - toluene diisocyanate , guinea pig , toluene , chemistry , immunology , medicine , polyurethane , organic chemistry
Guinea pigs were used to determine whether immunization and challenge by toluene diisocyanate (TDI) induce changes in the serum protein concentrations of the "acute-phase response" and whether TDI can form adducts with serum proteins.