Open AccessOccupational exposure to inhalative irritants and methacholine responsiveness
Author(s) -
Philippe Leuenberger,
Christian Schindler,
Joel Schwartz,
Ursula AckermannLiebrich,
D Tara,
AP Perruchoud,
B Wüthrich,
Zellweger Jp,
Kurt Blaser,
G Bolognini,
JP Bongard,
O Brändli,
Guido Domenighetti,
S Elsässer,
Leticia Grize,
Werner Karrer,
Roland Keller,
Nino Künzli,
Medici Tc,
Schöni Mh,
G Solari,
Tschopp Jm,
B Villiger,
Elisabeth Zemp
Publication year - 2000
Publication title -
scandinavian journal of work, environment and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.621
H-Index - 103
eISSN - 1795-990X
pISSN - 0355-3140
DOI - 10.5271/sjweh.524
Subject(s) - methacholine , atopy , medicine , asthma , allergy , occupational exposure , occupational asthma , immunology , respiratory disease , lung , environmental health
Occupational exposures to inhalative irritants have been associated with an increased reporting of respiratory symptoms in previous studies. Methacholine responsiveness represents a continuous measure of airway responsiveness. As such, it may be less subject to recall bias and more sensitive to detecting effects of occupational exposure on airways. Such effects may be stronger among atopic persons. The objective of the study was to examine the relationship between self-reports of occupational exposure to dusts, gases, vapors, aerosols, and fumes and methacholine responsiveness.