Open AccessAnalysis of urinary S-phenylmercapturic acid and trans,trans-muconic acid as exposure biomarkers of benzene in petrochemical and industrial areas of Korea
Author(s) -
Ming Fang,
Min Ki Shin,
Ki Wan Park,
Yoon Shin Kim,
Jeeyeon Lee,
MyungHaing Cho
Publication year - 2000
Publication title -
scandinavian journal of work, environment and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.621
H-Index - 103
eISSN - 1795-990X
pISSN - 0355-3140
DOI - 10.5271/sjweh.511
Subject(s) - muconic acid , urine , benzene , excretion , chemistry , biomonitoring , urinary system , environmental chemistry , intraperitoneal injection , toxicology , physiology , medicine , biochemistry , organic chemistry , biology
Recently, S-phenylmercapturic acid (S-PMA) and trans,trans-muconic acid (t,t-MA) in urine have been proposed as reliable biomarkers for monitoring occupational exposure to benzene. The aim of this study was to test the applicability of S-PMA and t,t-MA as exposure biomarkers and to monitor the occupational exposure level and the extent of environmental contamination from benzene in Korea.