Open AccessOccupational asbestos exposure and risk of oral cavity and pharyngeal cancer in the prospective Netherlands Cohort Study
Author(s) -
Nadine S M Offermans,
Roel Vermeulen,
Alex Burdorf,
R. Alexandra Goldbohm,
András Keszei,
Susan Peters,
Timo Kauppinen,
Hans Kromhout,
Piet A. van den Brandt
Publication year - 2014
Publication title -
scandinavian journal of work, environment and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.621
H-Index - 103
eISSN - 1795-990X
pISSN - 0355-3140
DOI - 10.5271/sjweh.3434
Subject(s) - asbestos , medicine , mesothelioma , prospective cohort study , hazard ratio , confidence interval , confounding , cohort study , population , job exposure matrix , environmental health , cancer , cohort , relative risk , pathology , materials science , metallurgy
The evidence for an association between occupational asbestos exposure and pharyngeal cancer (PhC) is limited, while for oral cavity cancer (OCC) the literature is even sparser. We studied OCC and PhC risk both separately and combined (OCPC) in relation to occupational asbestos exposure, specifically addressing the influence of potential confounders, the existence of an exposure-response relation, and the presence of interaction between asbestos and smoking.