Open AccessRotating-shift nurses after a day off: peripheral clock gene expression, urinary melatonin, and serum 17-β-estradiol levels
Author(s) -
Massimo Bracci,
Nicola Manzella,
Alfredo Copertaro,
Sara Staffolani,
Elisabetta Strafella,
Mariella Barbaresi,
Benedetta Copertaro,
Venerando Rapisarda,
Matteo Valentino,
Lory Santarelli
Publication year - 2014
Publication title -
scandinavian journal of work, environment and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.621
H-Index - 103
eISSN - 1795-990X
pISSN - 0355-3140
DOI - 10.5271/sjweh.3414
Subject(s) - morning , chronotype , melatonin , circadian rhythm , clock , medicine , shift work , endocrinology , peripheral , gene expression , breast cancer , peripheral blood , physiology , biology , cancer , circadian clock , gene , psychiatry , genetics
Impairment of clock gene expression and changes in melatonin and 17-β-estradiol levels may constitute biological alterations underlying the increased risk of breast cancer among shift workers. The aim of this study was to compare levels of selected core clock gene expression, 6-sulfatoxymelatonin (aMT6s), and 17-β-estradiol between rotational shift work (SW) and daytime (DT) workers after a day off.