Reduced lung cancer mortality and exposure to synthetic fluids and biocide in the auto manufacturing industry | Zendy

Amar Mehta | Zendy; Elizabeth J. Malloy | Zendy; Katie M. Applebaum | Zendy; Joel Schwartz | Zendy; David C. Christiani | Zendy; Ellen Eisen | Zendy

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Reduced lung cancer mortality and exposure to synthetic fluids and biocide in the auto manufacturing industry

Author(s) -

Amar Mehta,

Elizabeth J. Malloy,

Katie M. Applebaum,

Joel Schwartz,

David C. Christiani,

Ellen Eisen

Publication year - 2010

Publication title -

scandinavian journal of work environment and health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.621

H-Index - 103

eISSN - 1795-990X

pISSN - 0355-3140

DOI - 10.5271/sjweh.3088

Subject(s) - biocide , medicine , lung cancer , confidence interval , percentile , cohort , toxicology , biology , pathology , mathematics , statistics

Water-based soluble and synthetic metalworking fluids (MWF) used in auto manufacturing may be contaminated by endotoxin from Gram-negative bacteria, a possible anticarcinogen via increased immuno-surveillance. The effectiveness of biocide, generally added to limit bacterial growth is unknown. We investigated whether an inverse relationship between lung cancer and synthetic MWF and biocide - as surrogates of endotoxin exposure - persisted in an extended follow-up of autoworkers.

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