Open AccessReduced lung cancer mortality and exposure to synthetic fluids and biocide in the auto manufacturing industry
Author(s) -
Amar Mehta,
Elizabeth J. Malloy,
Katie M. Applebaum,
Joel Schwartz,
David C. Christiani,
Ellen A. Eisen
Publication year - 2010
Publication title -
scandinavian journal of work, environment and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.621
H-Index - 103
eISSN - 1795-990X
pISSN - 0355-3140
DOI - 10.5271/sjweh.3088
Subject(s) - biocide , medicine , lung cancer , confidence interval , percentile , cohort , toxicology , biology , pathology , mathematics , statistics
Water-based soluble and synthetic metalworking fluids (MWF) used in auto manufacturing may be contaminated by endotoxin from Gram-negative bacteria, a possible anticarcinogen via increased immuno-surveillance. The effectiveness of biocide, generally added to limit bacterial growth is unknown. We investigated whether an inverse relationship between lung cancer and synthetic MWF and biocide - as surrogates of endotoxin exposure - persisted in an extended follow-up of autoworkers.