
Methods for measuring trichloroethanol and trichloroacetic acid in blood and urine after exposure to trichloroethylene.
Author(s) -
Olof Vesterberg,
Jadviga Gorczak,
Mudite Krasts
Publication year - 1975
Publication title -
scandinavian journal of work, environment and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.621
H-Index - 103
eISSN - 1795-990X
pISSN - 0355-3140
DOI - 10.5271/sjweh.2842
Subject(s) - trichloroacetic acid , chemistry , chromatography , urine , trichloroethylene , chloroform , extraction (chemistry) , decarboxylation , gas chromatography , organic chemistry , biochemistry , catalysis
A description is given of procedures for the analysis of trichloroethanol, conjugated trichloroethanol, and trichloroacetic acid (TCA) in blood and urine. The determination of TCA is effected by measuring its decarboxylation product chloroform. The methods depend on extraction with isooctane and subsequent analysis by gas chromatography.