Open AccessTesting for mutagens in filter samples from the work atmosphere of an aluminum plant.
Author(s) -
Åse Krøkje,
Arne Tiltnes,
E. Mylius,
Barbro M. Gullvåg
Publication year - 1985
Publication title -
scandinavian journal of work, environment and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.621
H-Index - 103
eISSN - 1795-990X
pISSN - 0355-3140
DOI - 10.5271/sjweh.2224
Subject(s) - frameshift mutation , reversion , chemistry , anode , strain (injury) , food science , biochemistry , biology , mutation , gene , electrode , anatomy , phenotype
Filter extracts of airborne particles from a Söderberg potroom and an anode paste plant were tested for mutagenicity by the Salmonella reversion assay. The extracts were mutagenic to strains TA100 and TA98, mainly after metabolic activation, but positive results were obtained also without S9 mix in strain TA98. These findings indicate that the particulate phase of air from the potroom and the anode paste plant of aluminum plants contain mostly indirect mutagens of both the base-pair substitution and frameshift type, and--to a less degree--frameshift mutagens. The relationship between concentration and mutagenicity was more positive for the potroom extract than for the anode paste plant extract.