z-logo
open-access-imgOpen Access
Urinary styrene in the biological monitoring of styrene exposure.
Author(s) -
Fabriziomaria Gobba,
Claudia Galassi,
S Ghittori,
Marcello Imbriani,
Fabrizio Pugliese,
A Cavalleri
Publication year - 1993
Publication title -
scandinavian journal of work, environment and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.621
H-Index - 103
eISSN - 1795-990X
pISSN - 0355-3140
DOI - 10.5271/sjweh.1484
Subject(s) - styrene , mandelic acid , excretion , urine , chemistry , solvent , urinary system , chromatography , medicine , organic chemistry , biochemistry , polymer , copolymer
The urinary excretion of styrene represents a promising indicator of exposure to this solvent. Nevertheless extensive research under field conditions is scant. In this investigation 214 styrene-exposed workers from 10 fiberglass-reinforced plastics factories were studied. Environmental monitoring was performed by personal passive sampling. Blood styrene and the urinary excretion of styrene and its main metabolites, mandelic acid (MA) and phenylglyoxylic acid (PGA), were measured. The correlation coefficient between the time-weighted average of environmental styrene and the mean urinary excretion of styrene was 0.88 (0.91 after logarithmic transformation), compared with the 0.82 and 0.78 of the end-of-shift MA and PGA values, respectively. A high correlation (0.86) was also found between styrene in the blood and urine. The results, obtained under field conditions with a large group of exposed workers, confirm the usefulness of the urinary excretion of styrene as an exposure index for the biological monitoring of styrene exposure.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here