Open AccessNews in the diagnosis of gastric precancerous lesions
Author(s) -
Adriana Botezatu,
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Elmira Antoci,
Cezar Zagorneanu,
Mohamed Agbaria,
Nicolae Bodrug,
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AUTHOR_ID,
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Publication year - 2022
Publication title -
buletinul academiei de ştiinţe a moldovei: ştiinţe medicale
Language(s) - English
Resource type - Journals
ISSN - 1857-0011
DOI - 10.52692/1857-0011.2021.3-71.34
Subject(s) - atrophic gastritis , intestinal metaplasia , medicine , dysplasia , gastroenterology , precancerous condition , cancer , gold standard (test) , occult , biopsy , pathology , general surgery , gastritis , stomach , alternative medicine
Detection and close monitoring of patients with precancerous lesions - chronic atrophic gastritis (GCA), gastric intestinal metaplasia (MIG) and gastric mucosal epithelial dysplasia (DEMG) is a priority to increase early detection and, implicitly, decrease mortality and mortality. by gastric cancer (GC). The aim of the present study is to develop a narrative synthesis of contemporary studies on GCA diagnostic methods. Material and methods: Eligible studies were searched in the PubMed, Hinari, SpringerLink and Scopus (Elsevier) databases during the years 2000-2020. Results: Out of 575 articles addressing the topic of precancerous lesions, 59 articles were qualified representative for the materials published on the topic of this synthesis article. Conclusions: There are two main methodological approaches for GCA evaluation: non-invasive serological examination using gastric function markers and invasive examination, which requires histological analysis of biopsy samples taken during upper digestive endoscopy, the latter being the „gold standard” for diagnosis.