Open AccessEnergy metabolism inhibitors - a new group of antituberculous drugs
Author(s) -
Nicolae Bacinschi,
AUTHOR_ID,
Elena Tudor,
Mihaela Taraburca,
AUTHOR_ID,
AUTHOR_ID
Publication year - 2022
Publication title -
buletinul academiei de ştiinţe a moldovei: ştiinţe medicale
Language(s) - English
Resource type - Journals
ISSN - 1857-0011
DOI - 10.52692/1857-0011.2021.3-71.30
Subject(s) - tuberculosis , medicine , incidence (geometry) , patient compliance , adverse effect , pharmacology , intensive care medicine , pathology , emergency medicine , physics , optics
The treatment of tuberculosis, despite the intensification of research into new drugs, remains a current problem of phthisiopulmonology due to the emergence of mycobacteria with multiple and extensive resistance, decreased patient adherence to treatment due to long duration of treatment and side effects, transformation of mycobacteria into latent metabolic forms. Elucidation of new compounds influencing metabolism and energy processes opens new perspectives to optimize the treatment of TB-MDR and TB-XDR, as well as the development of new therapeutic regimens that would shorten the duration of treatment by reducing the incidence of adverse reactions and increasing patient compliance