Open AccessInfluence of compensation of selenium deficiency on immunological parameters of patients with multidrugresistant tuberculosis at the background of subclinical hypothyroidism
Author(s) -
S.L. Matvyeyeva,
AUTHOR_ID
Publication year - 2022
Publication title -
buletinul academiei de ştiinţe a moldovei: ştiinţe medicale
Language(s) - English
Resource type - Journals
ISSN - 1857-0011
DOI - 10.52692/1857-0011.2021.3-71.20
Subject(s) - subclinical infection , selenium , medicine , tuberculosis , selenium deficiency , thyroid , thyroid function , chemotherapy , thyroid function tests , immunology , endocrinology , gastroenterology , pathology , chemistry , glutathione peroxidase , catalase , oxidative stress , organic chemistry
In 60 patients with multidrug-resistant tuberculosis at the background of subclinical hypothyroidism serum level of selenium, thyroid state and immunological parameters were studied in dynamic of the intensive phase of chemotherapy. Initially low level of selenium, subclinical hypothyroidism and weaken immunological response toward tuberculosis were diagnosed. Prescribing of selenite sodium with 200 μ daily during 60 daily doses normalized serum level of selenium, restored thyroid function and improved immunological response. Using of selenite sodium like an accompanying medicine during chemotherapy of multidrug tuberculosis at the background of subclinical hypothyroidism after estimation of serum level of selenium is recommended.